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A Non-Inferiority Randomized Controlled Clinical Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Consequent to Military Sexual Trauma (MST) in Male and Female Military Personnel and Veterans

Clinical Trial Details

The purpose of this study is to compare two kinds of therapy for post-traumatic stress disorder (PTSD): exposure therapy (ET) and interpersonal psychotherapy (IPT). The results of this study will allow us to see if IPT and ET are equally effective in treating PTSD due to military sexual trauma, with the long-term goal of making PTSD treatment effective for as many people as possible. 

Key Eligibility: 

Inclusion Criteria

  • English-speaking
  • Age 18 to 70.
  • MST survivors from any service era, with any duty status and any discharge status (MST is defined as uninvited/unwanted sexual attention (such as touching, cornering, pressure for sexual favors, or verbal remarks), threat of or attempted 
    sexual contact, sexual assault, or any sort of sexual activity between at least two people in which one of the people is involved against his or her will.
  • Ability to attend weekly outpatient therapy sessions
  • Ability to provide informed consent and complete all assessment instruments
  • Stable on psychotropic medication for the prior 60 days

Exclusion Criteria

  • Lifetime or current diagnosis of schizophrenia or other psychotic disorder, bipolar disorder
  •  Participation in a clinical trial for MST-related psychiatric conditions or PTSD during the previous 3 months
  • Current evidence of significant unstable medical illness or organic brain impairment such that the patient could not attend sessions regularly or complete assessments
  • Patients who in the investigator’s judgment pose a current homicidal or suicidal risk
  • Current or history of substance dependence in the past 90 days

Study contact by location

Upper East Side - Manhattan


Mariel Emrich



Mariel Emrich

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:






Open to Enrollment

Age Group