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A Randomized Controlled Pilot Study of the Food Order Behavioral Intervention in Prediabetes

Clinical Trial Details

Our research concerns people who are overweight and have prediabetes. In previous studies, investigators found that food order during a meal had a positive effect on the ways bodies responded to food. When people ate vegetables and protein before eating carbohydrates, blood sugar and insulin (hormone that regulates blood sugar level) levels were lower than when they ate carbohydrates first. As was also the case when eating vegetable first, followed by protein and carbohydrates together. The purpose of this study is to assess what happens to blood sugar levels when practicing a carbohydrate-last meal order, along with standard nutrition counseling in subjects with prediabetes. Investigators are also looking to see if eating this way is a realistic possibility for people in an everyday setting. 

Key Eligibility: 
  • Male and female subjects who are 21 or older who have a BMI 25-40 and have been diagnosed with prediabetes 
  • Participants must be weight stable (5% body weight change over preceding 6 months) 
  • Participants must not have been diagnosed with type 2 diabetes, be on oral or injectable medications used to treat diabetes, use OTC or approved weight loss medications, be pregnant or lactating, or have undergone bariatric surgery 
  • Detailed eligibility will be reviewed when you contact the study team 

Study contact by location

Upper East Side - Manhattan


Anthony Joseph Casper
(646) 962-2424

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:




Open to Enrollment