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An evaluation of the safety and efficacy of a hydro soluble nail lacquer (Genadur®) for the treatment of simple brittle nails.

Clinical Trial Details

This study is investigating the affects of a prescription nail lacquer, Genadur®, on brittle nails. The nail lacquer contains natural substances and essential minerals that help protect the nails from losing moisture and damage from day‐to-day friction and trauma.

The treatment consists of a nightly application of the prescription nail lacquer to affected nails on one hand for 16 weeks with 3 doctor visits, with a 4-week follow up visit.

The study lasts approximately 20 weeks, including a screening visit, two visits 8 weeks apart, a 4 week follow up visit.

Patients will be compensated $100 for travel expenses and time.

Key Eligibility: 
  • Male or Female between the ages of 18-75
  • Have signs of Brittle nail syndrome (peeling/splitting of nails) of at least one finger nail(s) on EACH hands
  • Willing to give written informed consent and able to adhere to procedures, including a nail clipping to rule out concurrent nail fungus, and visit schedules
  • Are not currently undergoing any treatment for their brittle nail syndrome, including over-the-counter vitamins or lacquers.
  • Women of childbearing age must meet all the criteria above and agree to a pregnancy test

Study contact by location

Upper East Side - Manhattan


Sharmin Ferdaus

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:



Open to Enrollment

Age Group