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An Investigation of a Working Memory Training Program for Neurological Surgery Patients with Various Diagnoses

Clinical Trial Details

This study is for men and women who have undergone surgery for a neurological condition, including brain tumors, vascular disorders such as aneurysms or arteriovenous malformations, or elective surgery for epilepsy or Chiari malformation.
   
The purpose of this study is to determine the cognitive functioning of individuals after undergoing neurological surgery. Researchers are looking to measure the effects of a computerized working memory training program. The program will measure attention, memory and whether this program might help people who are having trouble with attention and memory cognitive problems.
   
This research is being done because there is a growing interest in survivorship and enhancing quality of life among patients surgically treated for a variety of neurological diagnoses. Cognitive functioning is a large part of quality of life after cancer treatment. Therefore, determining the impact of a computerized working memory training program on cognitive functioning is a significant part of the neurological surgery survivorship mission.
   
Participants will undergo a standard of care neuropsychological testing at three time points. This testing will assess participants’ memory, attention, and processing speed functions. The three time points are:
   
   • Time Point 1 - At the beginning of the study
   • Time Point 2 - After undergoing the research intervention
   • Time Point 3 - At three months after undergoing the research intervention
   
Participants will also complete computer program exercises. The computerized working memory training program will take place daily for forty-five (45) minutes for five (5) weeks at participant’s home computers. The computerized program is completed on an outpatient basis.
   
Participants will be in the study for 5 months.


Key Eligibility: 
  1. Undergone neurological surgery for a neurological condition, including brain tumors, vascular disorders such as aneurysms or arteriovenous malformations, or elective surgery for epilepsy or Chiari malformation.
  2. No evidence of disease progression at time of enrollment based on most recent clinical MRI scan and or clinical follow up

Detailed eligibility reviewed when participant contacts the study team.

Study contact by location

Upper East Side - Manhattan

Contact(s)

Amanda Sacks-Zimmerman, PhD, ABPP
212-746-3356
ams9095@med.cornell.edu

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:

1307014090

Status

Open to Enrollment

Age Group

Adult

Sponsor