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Assessing the effect of abstinence period on semen analysis parameters

Clinical Trial Details

The purpose of this study is to examine the effects of an abstinence period on semen parameters and sperm quality. There is no current data regarding the best time for men to produce a semen sample that will produce the highest quality sperm. This study aims to determine whether shorter abstinence periods may result in improved sperm quality.

Participants will be required to provide a total of 6 semen samples. The semen samples will be requested to be produced after 7 days, 5 days, 2 days, 1 day, and 3 hours of abstinence from sexual activity.

Samples will be analyzed using a variety of laboratory methods and personal identifiable information will be removed from this data. 

Participants will be required to come into the office for 6 study visits. Total study participation will last approximiately 15 days. 

Key Eligibility: 
  1. Open to healthy men aged 20-45 years with no significant co-morbidities 
  2. Participants must have a total sperm count of at least 1 million
  3. Participants must be able to produce semen samples by masturbation 

 Detailed eligibility will be reviewed when you contact the study team

Study contact by location

Upper East Side - Manhattan


Akeem Noziere

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:




Open to Enrollment

Age Group