Pfizer COVID-19 vaccine appointments are available to our patients. Sign up for Connect today to schedule your vaccination.

Comprehensive Assessment of Cancer Theranostics Response; Investigating the Intent to Change Treatment Decisions Based on TRAQinform Theranostics

Clinical Trial Details

This research study is for men who have a diagnosis of prostate cancer and have been selected by their physician to receive Pluvicto to treat their cancer.
   
This is a feasibility study that evaluates a software technology called TRAQinform Theranostics. The purpose of this study is to learn if more information (analysis) from the TRAQinform Theranostics software changes a physician’s understanding of treatment planning and how prostate cancer is responding to Pluvicto. The U.S. Food and Drug Administration (FDA) has not approved TRAQinform Theranostics for this specific disease, but it has been approved for other uses. It is considered investigational in this study.
   
TRAQinform Theranostics software automatically compares and analyzes imaging scans from the start of a participant’s treatment and during their treatment to provide more information to their physician. More information includes 1) visualization of individual lesions, 2) understanding which lesions are responding to treatment, and 3) understanding if critical organs are affected by the treatment.
   
For participants in this study, two Positron Emission Tomography and Computed Tomography (PET/CT) scans will be ordered and two diagnostic CTs will be ordered. The first PET/CT and diagnostic CT will be done before a participant starts Pluvicto and the second PET/CT and diagnostic CT will be done around 12 weeks after starting Pluvicto.

Participation in this study will last about 12 weeks.

Key Eligibility: 
  1. Men age 18 years or older with a diagnosis of metastatic prostate cancer.
  2. Planned to start 177Lu-PSMA (Pluvicto).
  3. Ability to tolerate two 68Ga-PSMA or 18F-DCFPyL PET/CT imaging procedures. One at baseline and at 12 weeks of 177Lu-PSMA (Pluvicto) treatment.

 Detailed eligibility will be reviewed when participants contact the study team

Study contact by location

Upper East Side - Manhattan

Contact(s)


646-962-2072
guonc@med.cornell.edu

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:

2408027787

Status

Open to Enrollment

Age Group

Adult

Disease