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Diet and Meal Timing in Patients with Non-Alcoholic Fatty Liver Disease: A Pilot Study

Clinical Trial Details

The purpose of this research study is to create diet and meal timing in patients with Non-Alcoholic Fatty Liver Disease. Time-Restricted Eating (TRE) is a form of caloric restriction through daily prolonged fasting that has been shown to lead to weight loss, improved glucose regulation, and suppression of inflammation. This study aims to test the hypothesis that TRE will add additional benefit in the treatment of NAFLD on top of standard of care diet and lifestyle modifications.

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disorders affecting over 30% of the general population and ~80% of patients with obesity and diabetes worldwide. The prevalence is increasing rapidly with the global epidemics of obesity and diabetes, making it the most common cause of liver disease in the United States. NAFLD is also an independent risk factor for cardiovascular disease, the number one cause of mortality in the U.S. As there are currently no U.S. Food and Drug Administration (FDA)-approved pharmacologic treatments for NAFLD, treatment recommendations focus on lifestyle modifications and weight management.

If an individual agrees to participate in this study and meets all the requirements, they will undergo diet and exercise counseling with diet recommendations. Participation in this study will last for up to 24 months.

Key Eligibility: 
  1. Men and women who are 18 years of age and older.
  2. Have been diagnosed with Non-alcoholic fatty liver disease (NAFLD)

Detailed eligibility reviewed when contacting the study team.
   

Study contact by location

Upper East Side - Manhattan

Contact(s)

Mallory Ianelli, RN, BSN
(646) 962-4040
mai2016@med.cornell.edu

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:

2110024103

Status

Open to Enrollment

Age Group

Adult

Sponsor