Pfizer COVID-19 vaccine appointments are available to our patients. Sign up for Connect today to schedule your vaccination.

Efficacy of Targeted App-Based Cognitive Behavioral Therapy for Anxiety and Depression

Clinical Trial Details

This study aims to learn how to best optimize a mobile iPhone Cognitive Behavioral Therapy (CBT) app, and whether a personalized mobile iPhone CBT program is more effective than a more comprehensive general mobile iPhone CBT program. Although the app is new, it is based on Cognitive Behavior Therapy, which is a traditional “gold-standard” behavior therapy approach to treat anxiety disorders.

Participants will be asked to use the app two times a week for about 20 minutes per session, and complete weekly virtual research assessments that range from 10 minutes to about 1.5 hours.

To help us learn about brain changes related to using the app, participants may also agree to optional MRI and/or EEG scans that occur before the start of the study, and 4 or 6 weeks later when finished using the app. 

Total study participation will last about 12 weeks. 

Key Eligibility: 
  1. Age between 18 and 25 years.
  2. Primary diagnosis of an anxiety, depressive disorder, or bipolar disorder 
  3. Not currently in Cognitive Behavioral Therapy (CBT)
  4. No change in dose of psychiatric medication in past 12 weeks or initiation of psychotherapy in the past 12 weeks. 

Detailed eligibility will be discussed with the study team.

Study contact by location

Upper East Side - Manhattan


Maddy Schier
646-289-5271 EXT 720

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:




Not Yet Recruiting

Age Group