Pfizer COVID-19 vaccine appointments are available to our patients. Sign up for Connect today to schedule your vaccination.

Engage & Connect: A novel, neuroscience-informed streamlined psychotherapy for postpartum depression

Clinical Trial Details

This study will test the effectiveness of Engage & Connect, a 9-week remotely delivered psychotherapy for postpartum depression that focuses on reducing social isolation and helping mothers engage in more pleasurable activities.  

Participants will be randomized to one of two groups, each consisting of 9 weekly therapy sessions. Randomization is like flipping a coin and there is a 50/50 chance of being assigned to either group.

One group will be treated with Engage & Connect, which is a psychotherapy aimed to increase engagement in rewarding social activities. The other group will be treated with a form of psychotherapy called Symptom Review and Psychoeducation (SRP), which provides helpful education on postpartum depression and a review of the emotional difficulties one faces during postpartum depression.

In both groups, participants will meet with a therapist weekly on Zoom.

Participants will also be asked to participate in 4 research assessments consisting of questions about mood, thoughts, and physical health.

Information shared with the study team is completely confidential and will not be shared with others outside of the team. We do not provide information to insurance companies or other entities.  

All participants will receive 9 weekly therapy sessions and there is no cost to participate. Compensation is available up to $120.

For more information and to have a member of the study team contact you, please fill out this form. 

Key Eligibility: 
  1. Open to all adults who have given birth in the last year
  2. Not currently in individual psychotherapy (not including support groups)
  3. No history or presence of psychiatric diagnoses other than depression, generalized anxiety disorder, or specific phobia
  4. Must reside in New York state

Detailed eligibility will be discussed with the study team.



Study contact by location

Upper East Side - Manhattan


Aliza Ayaz
646-289-5271 ext. 721

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:




Open to Enrollment

Age Group