Pfizer COVID-19 vaccine appointments are available to our patients. Sign up for Connect today to schedule your vaccination.

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

Clinical Trial Details

The purpose of this study is to test the safety and effectiveness of Exablate PTT (pallidothalamic tract) lesioning as a staged (2 procedures 6 months apart), bilateral (both sides of your brain) procedure to treat the motor complications in patients with idiopathic Parkinson's Disease (PD). The results of this study will help us determine whether ablation of PTT with focused ultrasound is a safe procedure in patients with idiopathic PD.

Key Eligibility: 
  • Open to men and women, age 30 years and older with a diagnosis of Parkinson's Disease (PD) as confirmed by a movement disorder neurologist.

  • Subjects must be on a stable dose of all PD medications for 30 days prior to screening visit PD assessments as determined by medical records

       Detailed eligibility will be reviewed when you contact the study team.

Study contact by location

Upper East Side - Manhattan


Kristin Strybing

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:






Open to Enrollment

Age Group