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MRI Detection of Carotid Plaques as a mechanism for embolic strokes of undetermined source (MRI DECIPHER)

Clinical Trial Details

The study is investigating a link between high-risk plaque and cardioembolic sources among patients with stroke of unknown causes. This observational study uses an MRI protocol to detect bleeds within plaque, a marker of high-risk plaque. There is an additional PET/MRI that patients can opt into to more closely observe the plaque within the carotid arteries.

This study includes optional parts which will have financial compensation.

Key Eligibility: 
  • Men and women 18 years or older with a diagnosis of ischemic stroke
  • The stroke must be classified as "cryptogenic" or with no known cause
  • Ability to participate in MRI scans
  • Cannot be pregnant or breastfeeding
  • Detailed eligibility will be reviewed when you contact the study team.

Study contact by location

Upper East Side - Manhattan


Carla Sherman
(646) 962-8284

Primary Investigator(s)

Protocol ID(s)

Weill Cornell Medicine IRB #:



Open to Enrollment

Age Group