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Joint Clinical Trials Office

Naltrexone Treatment for Prolonged Grief Disorder

Clinical Trial Details

This is a study to see how effective oral naltrexone is as treatment for prolonged grief disorder (PGD). Participants will take their assigned medication for 8 weeks, with monthly visits to assess symptom severity, social connectedness, and adverse reactions.

Key Eligibility: 
  • Open to men and women above the age of 18 who meet diagnostic criteria for prolonged grief disorder

  • Participants must not have any recent history of opioid dependence, liver disease, or currently pregnant

   
Detailed eligibility will be reviewed when you contact the study team.

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Study contact by location

Upper East Side - Manhattan

Contact(s)

James Gang
(215) 356-0697
jmg2016@med.cornell.edu

Primary Investigator(s)

Holly G Prigerson

Protocol ID(s)

Weill Cornell Medicine IRB #:

2004021873

ClinicalTrials.gov:

NCT04547985

Sponsor:

5R35CA197730-05

Status

Open to Enrollment

Age Group

Adult

Sponsor

  • National Institutes of Health (NIH)

Disease

Mental Health
Persistent Complex Bereavement Disorder
Prolonged Grief Disorder