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The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery. The mesh used is approved by the U.S. Food and Drug Administration (FDA).
Participants undergoing antireflux surgery will be assigned to one of two groups, a group that has surgery with mesh, or a group that has surgery without mesh.
Any required post-surgical visits will be standard-of-care visits that participants would have regardless of study participation.
Inclusion Criteria:
1. Documented diagnosis of gastroesophageal reflux disease
2. Adults aged 18 years or older
3. Participant is planned to undergo surgery for reflux disease
Exclusion
1. Known allergy to tetracycline hydrochloride or kanamycin sulfate
2. Pregnant
Detailed eligibility will be reviewed when you contact the study team.