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Prospective Evaluation of Nivolumab in Adjuvant Esophageal Carcinoma/Gastroesophageal Junction Cancer: A Non-interventional Study

This clinical trial is for men and women with early-stage esophageal cancer (EC) or gastroesophageal junction cancer (GEJC) who are currently receiving adjuvant nivolumab prior to and independently of participation in the study.

The purpose of this study is to learn more about patients with EC or GEJC who have started with nivolumab treatment and about the use and the effects of nivolumab in clinical practice. For this reason, BMS is conducting this study to collect additional information about:

Optimizing surgical decisions in young adults with breast cancer

The purpose of this study is to help us learn how best to support young women making decisions about breast cancer surgery.

Over the course of this study, a web-based decision support tool (“CONSYDER”) designed for women between the ages of 18-44 who are newly diagnosed with breast cancer and making decisions about breast cancer surgery, will begin to be offered as standard of care at each study site. Because sites will be provided access to CONSYDER at different times, some study participants will have access to the tool while others will not.

Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL)

Doctors know a lot about performing prostate surgeries. However, we are always trying to learn more and improve our skills for our patients' benefit. We want to try and make prostate surgeries safer, with fewer side effects for the patient, and look for a better way to remove cancer. In this study, we will monitor if there are problems after a participant's surgery. We will also document the results of the surgery and patient-reported quality of life.

Head and Neck Patient Registry

The purpose of this registry is to collect subject data, medical information, treatment data, and outcomes of patients treated by the Head and Neck Surgery Division in the Department of Otolaryngology at New York Presbyterian Hospital/Weill Cornell Medical Center. The intended use of this database is for research related to the evaluation, management, and outcomes of patients who were treated by our providers.

Diet and Meal Timing in Patients with Non-Alcoholic Fatty Liver Disease: A Pilot Study

The purpose of this research study is to create diet and meal timing in patients with Non-Alcoholic Fatty Liver Disease. Time-Restricted Eating (TRE) is a form of caloric restriction through daily prolonged fasting that has been shown to lead to weight loss, improved glucose regulation, and suppression of inflammation. This study aims to test the hypothesis that TRE will add additional benefit in the treatment of NAFLD on top of standard of care diet and lifestyle modifications.

Pain Reduction Using NEurostimulation (PRUNE) Study

The purpose of this study is to evaluate the usefulness of an at home small battery-operated device using a headband that delivers transcranial Direct Current Stimulation (tDCS) to see if it reduces pain in kidney disease patients receiving hemodialysis (HD) treatments.

The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing the Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients with Locally Advanced Rectal Cancer

This study is being done to evaluate if by adding a 3rd drug (irinotecan) to the standard regimen of FOLFOX or CAPOX given following long-course chemoradiation for patients with locally advanced rectal cancer can increase the clinical complete response rate (tumor disappears by exam, endoscopy, and imaging).

The usual approach for patients who are not in a study is treatment with chemoradiation followed by radical surgery then possibly chemotherapy after surgery, or a combination of chemotherapy then chemoradiation then radical surgery.