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Preserving Erectile Function by Quantifying the Nerve-Sparing Step of the Robotic Prostatectomy

Our broad objective is to quantify surgeon performance, build automated assessments grounded in patient-centered outcomes, and develop quality assurance programs to improve training for surgeons.
   

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients with Advanced Melanoma

The purpose of this research study is to compare any good and bad effects of giving ipilimumab, nivolumab, and GM-CSF (Sargramostim) at the same time compared to just ipilimumab and nivolumab together for advanced melanoma. It would also like to find out what effects, good and bad, this combination of drugs may have on the cancer. 

A Phase 1/2, Open Label, Dose Escalation and Expansion Study of TAC-001 in Patients with Select Advanced or Metastatic Solid Tumors

This clinical trial is for men and women with advanced cancer or cancer that has spread to other parts of the body, and have either not tolerated the standard therapy, or there is no standard therapy available.

The purpose of this study is to test the safety of an investigational (experimental) drug, TAC-001, to see what effects it has on the cancer. Investigational means that it is not yet approved by the U.S. Food and Drug Administration (FDA). 

In Vivo Evaluation of Lymph Nodes Using Quantitative Ultrasound

The purpose of this study is to determine the effectiveness of a new ultrasound technique to detect cancer and/or other abnormalities in lymph nodes, small bean-shaped structures that are part of the body's immune system. Participants in this study will have at least one lymph node that may be larger than normal. 

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

The purpose of this study is to test the safety and effectiveness of the experimental combination of tazemetostat with chimeric antigen receptor t-cell (CAR T) cell therapy, and see what effects it has on lymphoma. An additional purpose of this study is to understand what side effects people may have when they receive both drugs together.

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Magrolimab versus Placebo in Combination with Venetoclax and Azacitidine in Newly Diagnosed, Previously Untreated Patients with Acute Myeloid Leukemia Who

This clinical trial is for men and women with newly diagnosed Acute Myeloid Lymphoma (AML) who are not eligible for intensive chemotherapy.
   
The purpose of this study is to evaluate the safety and effectiveness of the addition of an experimental drug, magrolimab, in combination with venetoclax and azacitidine compared to venetoclax and azacitidine alone.
   
Experimental means that magrolimab has not yet been approved by the U.S. Food and Drug Administration (FDA).
   

A Randomized Double-blind Placebo-controlled Phase 3 Study to Evaluate the Effect of Resmetirom on Liver-related Outcomes in Patients with Well-compensated (Child-Pugh A) Non-alcoholic Steatohepatitis (NASH) Cirrhosis (MAESTRO-NASH OUTCOMES)

This study is being conducted to learn more about the effects and safety of the investigational/experimental study drug MGL-3196 (resmetirom) and compare the study drug with placebo in men or women who have been diagnosed with Non-Alcoholic Steatohepatitis (NASH). 
   
An investigational/experimental study drug is one that has not been approved by the Food and Drug Administration (FDA).