Seeded Cells on Matrix Plug Treating Crohn’s Perianal Fistulas (STOMP-II)

The purpose of this research study is to determine whether the investigational product, AVB-114, is safe and effective to treat perianal fistulas in people with Crohn’s disease.

Pilot Study of PSMA-TRT Re-treatment Utilizing 225Ac-J591

This is a pilot study of single dose of 225Ac-J591 at 90 KBq/Kg in men with progressive metastatic castration resistant prostate cancer (mCRPC).

A Phase IIb, Open-label, Randomized Study of Nab-Paclitaxel and Gemcitabine plus/minus VCN-01 in Patients with Metastatic Pancreatic Cancer

The study will test an investigational product called VCN-01 in patients with metastatic pancreatic cancer. “Investigational” means that VCN-01 has not been approved by the U.S. Food and Drug Administration (FDA) to treat any disease.

Preserving Erectile Function by Quantifying the Nerve-Sparing Step of the Robotic Prostatectomy

Our broad objective is to quantify surgeon performance, build automated assessments grounded in patient-centered outcomes, and develop quality assurance programs to improve training for surgeons.
   

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients with Advanced Melanoma

The purpose of this research study is to compare any good and bad effects of giving ipilimumab, nivolumab, and GM-CSF (Sargramostim) at the same time compared to just ipilimumab and nivolumab together for advanced melanoma. It would also like to find out what effects, good and bad, this combination of drugs may have on the cancer. 

A Phase 1/2, Open Label, Dose Escalation and Expansion Study of TAC-001 in Patients with Select Advanced or Metastatic Solid Tumors

This clinical trial is for men and women with advanced cancer or cancer that has spread to other parts of the body, and have either not tolerated the standard therapy, or there is no standard therapy available.

The purpose of this study is to test the safety of an investigational (experimental) drug, TAC-001, to see what effects it has on the cancer. Investigational means that it is not yet approved by the U.S. Food and Drug Administration (FDA). 

In Vivo Evaluation of Lymph Nodes Using Quantitative Ultrasound

The purpose of this study is to determine the effectiveness of a new ultrasound technique to detect cancer and/or other abnormalities in lymph nodes, small bean-shaped structures that are part of the body's immune system. Participants in this study will have at least one lymph node that may be larger than normal.