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Joint Clinical Trials Office

Pediatric Inflammatory Bowel Disease (IBD) Biobank

This research study is being conducted by Dr. Robbyn Sockolow, MD, the director of Pediatric Gastroenterology and Nutrition at Weill Cornell Medical College (WCM) and Komansky Children’s Hospital, and Dr. David Artis, PhD, the director of the Jill Roberts Institute for IBD at WCM. Their teams are looking for pediatric patients who are undergoing a colonoscopy or intestinal surgery.

Why is the study being done?
We are learning about the factors underlying inflammatory bowel disease with the hope that we may improve the care of pediatric patients. 

Research Registry - Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry (IPF-PRO)

The Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry (IPF-PRO)  aims to:

  • Collect information regarding the natural history of IPF and healthcare interactions
  • Describe quality of life of IPF participants with patient reported questionnaires
  • Assess the methods of treatment of participants
  • Collect blood specimens for future research projects

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

CREST-2 is a study for people who have narrowing of their carotid artery without symptoms caused by that artery like small strokes or temporary strokes. Temporary strokes are often called transient ischemic attacks or TIAs. The purpose of this study is to compare intensive medical management alone to intensive medical management plus a procedure to reopen the carotid artery in the neck for treatment of plaque buildup.

Remission without Admission

Dr. Roboz and AML Patient enrolled in clinical trial
Dr. Roboz and AML Patient Ralph Hills
In 2014, Ralph Hills was diagnosed with acute myeloid leukemia (AML) and his doctors told him to “get your affairs in order." Everything changed when he enrolled in an innovative clinical trial. Learn about the treatment that put his cancer into remission without requiring him to be admitted to the hospital.

There's an App for That

Dr. Deborah Estrin Photo credit: John Abbott
Dr. Deborah Estrin Photo credit: John Abbott

Last year, Apple unveiled a new platform that offers a streamlined way to create mobile applications linked to medical research. The technology, called ResearchKit, lets investigators more easily connect with the people whose diseases they're studying, allowing them to gather feedback on symptoms, as well as data on everything from a patient's weight to the air quality where they live.

Researchers Develop Method to Identify Patient-Specific Drugs for Treating Diabetes

This image shows human embryonic stem cell-derived pancreatic beta cell clusters after being transplanted into immunodeficient mice. Image credit: Drs. Hui Zeng and Min Guo
This image shows human embryonic stem cell-derived pancreatic beta cell clusters after being transplanted into immunodeficient mice. Image credit: Drs. Hui Zeng and Min Guo

An innovative method that uses human embryonic stem cells to model type 2 diabetes caused by genetic mutations may enable researchers to identify drugs that could treat the disease. The research by Weill Cornell Medicine investigators was published Aug. 11 in Cell Stem Cell, and may extend the use of precision medicine to metabolic diseases.

We Are Weill Cornell Medicine: Dr. Olivier Elemento

Dr. Oliver Elemento
Dr. Oliver Elemento

Computational biologist Dr. Olivier Elemento was just 6 years old when he received his first microscope and computer. Now he is harnessing the power of both to spot patterns and trends in cancer that could help doctors treat the disease — and perhaps even find a cure.

Tall Order

Office visit: Pediatrician Dr. Thomas Ciecierega with Alex and his family.
Office visit: Pediatrician Dr. Thomas Ciecierega with Alex and his family.

AN AMBITIOUS STUDY AIMS TO UNDERSTAND HOW CROHN'S DISEASE STUNTS KIDS' GROWTH

Eventually, Alex's parents brought him to NewYork-Presbyterian/Weill Cornell Medical Center, where he saw Dr. Thomas Ciecierega, an assistant professor of pediatrics. Dr. Ciecierega made the correct diagnosis — Crohn's disease, a type of inflammatory bowel disease (IBD) that is characterized by intestinal inflammation — and put the boy on the proper course of medication.

New Big Data Approach Predicts Drug Toxicity in Humans

Dr. Olivier Elemento Photo credit: Roger Tully
Dr. Olivier Elemento Photo credit: Roger Tully

Researchers can now predict the odds of experimental drugs succeeding in clinical trials, thanks to a new data-driven approach developed by Weill Cornell Medicine scientists. The method detects toxic side effects that may disqualify drugs from human use, giving drug developers an early warning before initiating clinical trials, according to a new study published Sept. 15 in Cell Chemical Biology.

Why is a clinical trial so important?

Dr. John Leonard
Dr. John Leonard

Virtually every advance we have in medicine, virtually everything we do to try to improve outcomes for patients or understand their illnesses comes from clinical trials. So it is really an essential part of moving medicine forward and moving treatments forward to provide better care for patients.

To learn more about clinical trials and the importance of futhering research [go]