This research study is being conducted to better understand how the Eye90 radiation treatment affects liver tumors.

After a patient undergoes transplant surgery, the removed liver tissue will be examined using detailed imaging and microscope techniques to study how well the treatment worked and how the radiation particles were distributed in the tumor.

No additional tests, procedures, or visits are required for participation in this study.

Vitiligo is a long-term autoimmune condition that causes the skin to lose its color. The body's germ-fighting system (immune system) mistakenly attacks the skin cells (melanocytes) which produce the pigment that gives the skin color (melanin). This leads to the formation of patches of skin with less or no pigment (depigmentation). These patches can occur anywhere on the body. In the nonsegmental form of vitiligo, similar patches occur on both sides of the body (symmetrical patches).

Vitiligo is a long-term autoimmune condition that causes the skin to lose its color. The body's germ-fighting system (immune system) mistakenly attacks the skin cells (melanocytes) which produce the pigment that gives the skin color (melanin). This leads to the formation of patches of skin with less or no pigment (depigmentation). These patches can occur anywhere on the body. In the nonsegmental form of vitiligo, similar patches occur on both sides of the body (symmetrical patches).

This trial compares the effect of two different types of coaching for people living with Rheumatoid Arthritis (RA). Living with RA is difficult, and some people will also experience challenges with stress, anxiety, and difficult emotions (depressive or sad symptoms).

The main purpose of this study is to investigate whether the study drug, trontinemab, is able to slow down the worsening of symptoms in participants with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia. 

Trontinemab combines an anti-amyloid antibody with a module that helps deliver the antibody more efficiently to the brain. Once in the brain, trontinemab works by removing amyloid-beta plaques, a protein associated with Alzheimer’s disease.

The purpose of this prescreening study is to identify people that may be eligible for future clinical trials that test new drugs for Alzheimer’s disease.

This clinical research study aims to investigate the safety and efficacy of a study drug called vonoprazan, a potassium-competitive acid blocker, for treating Eosinophilic Esophagitis (EoE). EoE is characterized by an excessive presence of eosinophils in the esophagus, leading to inflammation and symptoms such as difficulty swallowing, chest pain, and nausea. The main objective of the study is to assess the effectiveness of vonoprazan in alleviating the symptoms of EoE and improving patient outcomes.

The purpose of this study is to evaluate the safety and effectiveness of AAA817 and an Androgen receptor pathway inhibitor (ARPI) given compared to the standard of care options.
   
AAA817 is experimental, which means it is being tested and is not yet approved by the United States Food and Drug Administration (FDA).
   
In this study, AAA817 will be given intravenously (meaning through a needle in the vein directly into the blood). The Androgen receptor pathway inhibitor (ARPI) will be given orallly.

This project hopes to learn about the impact of high cholesterol in patients with primary biliary cholangitis. Participants wil have primary biliary cholangitis and elevated cholesterol levels.

Primary biliary cholangitis is a chronic, cholestatic liver disease that results in progressive fibrosis and ultimately cirrhosis 

The purpose of this study is to evaluate the safety and effectiveness of Ziftomenib (KO-539) in patients with acute myeloid leukemia (AML). This study has 2 separate investigations (Nonintensive and Intensive).