This study will test the effectiveness of Engage & Connect, a 9-week remotely delivered psychotherapy for postpartum depression that focuses on reducing social isolation and helping mothers engage in more pleasurable activities.

Participants will be randomized to one of two groups, each consisting of 9 weekly therapy sessions. Randomization is like flipping a coin and there is a 50/50 chance of being assigned to either group.

Atypical choroid plexus papilloma (ACPP) and choroid plexus carcinoma (CPC) are both primary brain tumors that begin near the brain tissue. Choroid plexus carcinoma is fast-growing high-grade tumor, whereas atypical choroid plexus papilloma is an intermediate-grade tumor.

Removing these tumors through surgery has the best outcome for patients with ACPP or CPC, but there are often complications that can occur during the surgery. 

This is a clinical trial for adults with advanced solid tumors that have continued to grow despite the treatments already received.

The purpose of this study is to test a novel assessment of social feedback in adults with depression. It aims to study the association between activity levels, mood, and social aspects of life over the course time.

The purpose of this study is to evaluate a study drug called CFI-400945, either by itself or in combination with one of two chemotherapy drugs, known as azacitidine or decitabine. The study aims to determine how safe this drug is at different doses, with food, and in combination with azacitidine or decitabine, and to measure how well each combination works for acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myelomonocytic leukemia (CMML).

The purpose of this study is to look at combining the study drug IMGN632 with standard therapies (azacitidine and/or venetoclax) for acute myeloid leukemia (AML). The study will look at what effects (both good and/or bad) this combination has on the cancer, how well this combination works to treat cancer, and what a safe dose of the study drug is.

IMGN5632 is considered experimental, meaning it has not yet been approved by the U.S. Food and Drug Administration (FDA) or other health authorities.

Participants will receive IMGN5632 in combination with venetoclax andazacitidine.

This is a clinical trial for adults who have been diagnosed with relapsed or refractory multiple myeloma.
   

The purpose of the study is to see if short course radiation treatment to the tumor combined with two investigational drugs AB928 and AB122 will help in eliminating the tumor and thereby increase response to the treatment in patients with rectal cancer.
   

This is a randomized study comparing 5 radiation therapy treatments to 2 radiation therapy treatments with MRI guidance in patients with prostate cancer. The study will assess the potential benefit of limiting radiation doses received by normal tissues, namely the bladder and the rectum, with advanced MRI image guidance and to compare urinary and bowel side effects between the two treatment options.  Prostate cancer cure and control and quality of life will also be examined. 

Learn more about the trial details in this informational video: