The purpose of this study is to evaluate physical reactions associated with PTSD that develops due to the experience of military sexual trauma.

We are conducting a randomized proof-of-concept study to assess the efficacy of virtual reality (VR) vs standard of care in 50 adult patients in the NewYork-Presbyterian Burn Unit. The participants who are randomized to receive the virtual reality intervention will also receive opioids, which is the standard of care and is known to be effective.

The purpose of this study is to treat symptoms of posttraumatic stress disorder (PTSD) resulting from burn trauma using traditional treatment. 

Military sexual trauma (MST) is defined as uninvited/unwanted sexual attention (such as touching, cornering, pressure for sexual favors, or verbal remarks), threat of or attempted 
sexual contact, sexual assault, or any sort of sexual activity between at least two people in which one of the people is involved against their will. This research is being done because MST has been identified as a pervasive problem with profound psychological and physical consequences.

Depression is the second leading cause of disability worldwide, due partly to the fact that existing antidepressants are not effective for all patients and it is often challenging to match individual patients to the treatments that are most likely to help them. This study will test a new strategy for using fMRI brain scans to predict antidepressant response and assist clinicians in choosing antidepressant treatments. Transcranial magnetic stimulation targeting one of two depression-related brain areas is most likely to benefit an individual patient. 

The goal of this study is to learn about changes in the brain of older adults that occur during treatment for depression with two types of psychotherapy called Engage therapy and supportive therapy, and how they differ from one another.

Engage therapy is designed to help individuals with depression become involved in activities they previously enjoyed but have not been participating in since developing depression. In Engage therapy, individuals with depression work with a therapist to develop "action plans" to pursue rewarding activities of their choice.

The purpose of this study is to compare thinking, emotions, and brain function in older adults without a history of psychiatric illness to older adults who are receiving treatment for depression in our other studies. This research is being done to help develop, understand, and improve treatments for depression in older adults. In order to help benefit people with depression in the future, we also need to evaluate older adults with no history of depression.

Hemophilia B is an inherited (genetic) disease in which a protein (factor IX) that promotes blood clotting is missing or does not work properly. Hemophilia B is caused by a defect in the gene that produces the factor IX protein. Factor IX protein is important in blood clotting. Patients with severe hemophilia B have very low levels of the normal factor IX protein. Such low levels can result in spontaneous bleeding events that cause destruction of bone and tissue. 

YELLOWSTONE Induction Study (RPC01-3201): This study is designed to determine the safety and effectiveness of the oral investigational study drug, ozanimod, versus a placebo (an inactive substance) in achieving symptom remission in patients with active Crohn's disease symptoms. An induction study is the first in a series of studies. Participation in this clinical study is expected to last 12 weeks (3 months). 

This clinical trial is for men age 18 and older with prostate cancer to check safety and tolerability of IMMU-132.