The purpose of this study is to determine the effect of single vs. multiple arterial revascularization (this is the restoration of blood flow to an organ) for patients undergoing coronary artery bypass surgery. 

 The purpose of this study is to continue to learn about impact of comprehensive care on the natural history of patients with thalassemia (Cooley’s anemia) and other severe anemias requiring periodic or regular red blood cell transfusions. We will collect data on guideline recommended measures obtained from the standard of care: routine tests (EKG, Echocardiogram, Holter Monitor, MRI, eye exam, hearing test, x-ray, bone studies, pulmonary function study) done once a year and monthly blood draw and urinalysis for complete blood count, chemistries, and iron studies.

This is a prospective, multi-center, observational study designed to determine if specific agents used for treatment of inflammatory bowel disease (IBD) are associated with the development of new or recurrent cancer in patients with IBD and a history of cancer.

 Commitments for enrollment include:

The goal of this clinical research study is to assess whether the combination of BP1001 and cytarabine provides greater efficacy (Complete Remission [CR], Complete Remission with incomplete hematologic recovery [CRi], Complete Remission with incomplete platelet recovery [CRp]) than cytarabine alone (by historical comparison) in participants with AML that cannot or elect not to be treated with more intensive chemotherapy.

In this protocol, we plan to prospectively recruit subjects with chronic kidney disease or end stage kidney disease on dialysis. We will obtain stool, blood, urine (if possible), and peritoneal fluid (if on peritoneal dialysis) from the subjects on a regular basis and we will correlate whether the microbiome in these biospecimens are associated with and/or predictive of bacteremia and other complications in chronic kidney disease and end stage kidney disease.

This is a retrospective and prospective study to study the use of MRI prostate imaging and other patient characteristics such as PSA and commercially available assays and its accuracy in predicting the grade and location of prostate cancer during prostate needle biopsy as well as radical prostatectomy for men going onto surgery. 

This research study is being conducted by Dr. Robbyn Sockolow, MD, the director of Pediatric Gastroenterology and Nutrition at Weill Cornell Medical College (WCM) and Komansky Children’s Hospital, and Dr. David Artis, PhD, the director of the Jill Roberts Institute for IBD at WCM. Their teams are looking for pediatric patients who are undergoing a colonoscopy or intestinal surgery.

Why is the study being done?
We are learning about the factors underlying inflammatory bowel disease with the hope that we may improve the care of pediatric patients. 

The Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry (IPF-PRO)  aims to:

• Collect information regarding the natural history of IPF and healthcare interactions
• Describe quality of life of IPF participants with patient reported questionnaires
• Assess the methods of treatment of participants
• Collect blood specimens for future research projects

CREST-2 is a study for people who have narrowing of their carotid artery without symptoms caused by that artery like small strokes or temporary strokes. Temporary strokes are often called transient ischemic attacks or TIAs. The purpose of this study is to compare intensive medical management alone to intensive medical management plus a procedure to reopen the carotid artery in the neck for treatment of plaque buildup.

This clinical trial is for men and women with high-grade gliomas. Glucose (sugar) is thought to be a contributor to tumor growth. The ketogenic diet (a high fat, low carbohydrate diet) and metformin (a drug approved by the Food and Drug Administration to treat type 2 diabetes) are both known to lower blood glucose levels.