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The Multi-Center African American IBD Study (MAAIS)

This research study is for men and women who are of African American descent and who:

  • Have Inflammatory Bowel Disease (IBD)
  • Have a family member with IBD
  • Do not have IBD or a family member with IBD (for comparison)

The purpose of the study is to find out why inflammatory bowel disease (Crohn’s disease and ulcerative colitis) occurs in individuals and families of African-American descent. The research is being done because the characteristics of IBD in the African-American population have not been well documented.

Phase 3 Randomized Study of the Efficacy and Safety of Posaconazole versus Voriconazole for the Treatment of Invasive Aspergillosis in Adults

To compare the global clinical response of posaconazole (POS) compared to voriconazole (VOR) in the first line treatment of invasive aspergillosis (IA) at Week 6 in those subjects with proven or probable IA. The hypothesis to be tested is that the proportion of subjects achieving the global clinical response at Week 6 in the POS treatment group is noninferior to that in the VOR treatment group.

POS was shown to be effective in an open label, externally controlled salvage therapy trial of 107 patients with proven/probable aspergillosis.