We are conducting a randomized proof-of-concept study to assess the efficacy of virtual reality (VR) vs standard of care in 50 adult patients in the NewYork-Presbyterian Burn Unit. The participants who are randomized to receive the virtual reality intervention will also receive opioids, which is the standard of care and is known to be effective.

The purpose of this study is to treat symptoms of posttraumatic stress disorder (PTSD) resulting from burn trauma using traditional treatment. 

Military sexual trauma (MST) is defined as uninvited/unwanted sexual attention (such as touching, cornering, pressure for sexual favors, or verbal remarks), threat of or attempted 
sexual contact, sexual assault, or any sort of sexual activity between at least two people in which one of the people is involved against their will. This research is being done because MST has been identified as a pervasive problem with profound psychological and physical consequences.

Depression is the second leading cause of disability worldwide, due partly to the fact that existing antidepressants are not effective for all patients and it is often challenging to match individual patients to the treatments that are most likely to help them. This study will test a new strategy for using fMRI brain scans to predict antidepressant response and assist clinicians in choosing antidepressant treatments. Transcranial magnetic stimulation targeting one of two depression-related brain areas is most likely to benefit an individual patient. 

This clinical trial is for men age 18 and older with metastatic castration-resistant prostate cancer (mCRPC), which is prostate cancer that no longer responds to hormone therapy. The cancer spreads (metastasizes) to the bones. 

Standard treatment for advanced germ cell tumors includes three chemotherapy drugs called BEP (Bleomycin, Etoposide, and cisPlatin). BEP is given with a drug called pegfilgrastim or filgrastim which makes white blood cells grow. These drugs are given over the course of 3 weeks. Previous research has been done in studying BEP to improve the outcome of patients with poor-risk GCTs. One method that was tried is called dose intensification. This method works by giving the dose of chemotherapy drugs over a shorter length of time.

Breast cancer subjects with multiple brain metastases are often initially treated with stereotactic radiosurgery (SRS), a non-surgical radiation technique used to treat small brain tumors or whole brain radiation therapy (WBRT). When initially managed with SRS, subjects often develop new brain metastases in the untreated brain, requiring additional SRS procedures and, eventually, WBRT, which is often associated with significant neurocognitive sequelae (headache, nausea, dizziness, confusion, memory loss and motor dysfunction).

This is an observational study for men and women who have a body mass index (BMI) of greater than 30 kg/m2 and have a history of liver or gastrointestinal (GI) problems. 

This clinical trial is open to adult men and women age 60 and under who are newly diagnosed with FLT3 Mutated Acute Myeloid Leukemia (AML). 

The purpose of this study is to test the safety of the combination of multiple drugs: brentuximab vedotin which is approved for use in relapsed Hodgkin lymphoma, ipilimumab and nivolumab both drugs which stimulate your immune system, and which are approved for use in other cancers, but are investigational for Hodgkin lymphoma.